Social, economic, and access to services factors influencing non-prescription antibiotic use in island communities: A Qualitative study
Keywords:
access to health services, economic factors, island communities, non-prescription antibiotics, social factorsAbstract
Background: The use of antibiotics without a prescription remains a public health problem because it can increase inappropriate drug use and accelerate antimicrobial resistance. In island communities, this behavior is not only influenced by knowledge, but also by treatment experience, family norms, economic capacity, distance between islands, sea transportation, weather, and service availability. This study aims to explore social, economic, and service access factors that underlie the use of antibiotics without a prescription in the community. Methods: The study used an exploratory qualitative case study design with a constructivist-interpretive paradigm. Informants were selected purposively with maximum variation, consisting of 20 community members who had obtained or used antibiotics without a prescription and seven key informants. Data were collected through in-depth interviews, non-participant observation, and document review. The analysis was conducted through data condensation, inductive-deductive coding, matrix presentation, thematic analysis, source triangulation, and conclusion verification. Findings: Five main themes were identified, antibiotics are perceived as a powerful medicine based on recovery experiences; family and social networks shape usage decisions; direct and indirect costs influence treatment choices; geographic and operational barriers limit access to community health centers; and the use of antibiotics without a prescription becomes a pragmatic strategy when services are difficult to access. These findings indicate that positive attitudes toward previous experiences, social norms, and perceived ease of access to antibiotics reinforce the use of antibiotics without a prescription. The integration of the theory of planned behavior and the service access framework explains the relationship between individual decisions and structural barriers in local island communities. Conclusions: The use of antibiotics without a prescription in island communities is shaped by the interaction of individual experiences, social norms, economic burdens, and limited access. Novelty/Originality of this article: The study provides a community-based framework for addressing non-prescription antibiotic use by integrating educational interventions, mobile services, pharmaceutical service strengthening, and strategies to reduce transportation barriers and indirect costs.
References
Ajzen, I. (1991). The theory of planned behavior. Organizational Behavior and Human Decision Processes, 50(2), 179–211. https://doi.org/10.1016/0749-5978(91)90020-T.
Belay, W. Y., Getachew, M., Tegegne, B. A., Teffera, Z. H., Dagne, A., Zeleke, T. K., ... & Aschale, Y. (2024). Mechanism of antibacterial resistance, strategies and next-generation antimicrobials to contain antimicrobial resistance: a review. Frontiers in pharmacology, 15, 1444781. https://doi.org/10.3389/fphar.2024.1444781
Boiko, O., Gulliford, M. C., & Burgess, C. (2020). Revisiting patient expectations and experiences of antibiotics in an era of antimicrobial resistance: Qualitative study. Health Expectations, 23(5), 1250-1258. https://doi.org/10.1111/hex.13102
Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77–101. https://doi.org/10.1191/1478088706qp063oa
Cabral, C., Zhang, T., Oliver, I., Little, P., Yardley, L., & Lambert, H. (2024). Influences on use of antibiotics without prescription by the public in low- and middle-income countries: A systematic review and synthesis of qualitative evidence. JAC-Antimicrobial Resistance, 6(5), dlae165. https://doi.org/10.1093/jacamr/dlae165
Cai, H. T. N., Tran, H. T., Nguyen, Y. H. T., Vu, G. Q. T., Tran, T. P., Bui, P. B., ... & Lewycka, S. (2022). Challenges and lessons learned in the development of a participatory learning and action intervention to tackle antibiotic resistance: Experiences from northern Vietnam. Frontiers in Public Health, 10, 822873. https://doi.org/10.3389/fpubh.2022.822873
Central Statistics Agency of Pangkajene and Kepulauan Regency. (2025). Kecamatan Liukang Tupabbiring dalam angka 2025. Badan Pusat Statistik Kabupaten Pangkajene dan Kepulauan. https://pangkepkab.bps.go.id/id/publication/2025/09/26/0d9f3c9ab97068d4d87a1d66/kecamatan-liukang-tupabbiring-dalam-angka-2025.html
Ferdiana, A., Liverani, M., Khan, M., Wulandari, L. P. L., Mashuri, Y. A., Batura, N., Wibawa, T., Yeung, S., Day, R., Jan, S., Wiseman, V., & Probandari, A. (2021). Community pharmacies, drug stores, and antibiotic dispensing in Indonesia: A qualitative study. BMC Public Health, 21, 1800. https://doi.org/10.1186/s12889-021-11885-4
Kolář, M. (2022). Bacterial infections, antimicrobial resistance and antibiotic therapy. Life, 12(4), 468. https://doi.org/10.3390/life12040468
Ledingham, K., Hinchliffe, S., Jackson, M., Thomas, F., & Tomson, G. (2019). Antibiotic resistance: using a cultural contexts of health approach to address a global health challenge. World Health Organization. Regional Office for Europe.
Lempert, R. J., Busch, L., Brown, R., Patton, A., Turner, S., Schmidt, J., & Young, T. (2023). Community-level, participatory co-design for landslide warning with implications for climate services. Sustainability, 15(5), 4294. https://doi.org/10.3390/su15054294
Leosari, Y., Uelmen, J. A., & Carney, R. M. (2023). Spatial evaluation of healthcare accessibility across archipelagic communities of Maluku Province, Indonesia. PLOS Global Public Health, 3(3), e0001600. https://doi.org/10.1371/journal.pgph.0001600
Levesque, J. F., Harris, M. F., & Russell, G. M. (2013). Patient-centred access to health care: Conceptualising access at the interface of health systems and populations. International Journal for Equity in Health, 12, 18. https://doi.org/10.1186/1475-9276-12-18
Limato, R., Lazarus, G., Dernison, P., Mudia, M., Alamanda, M., Nelwan, E. J., Sinto, R., Karuniawati, A., van Doorn, H. R., & Hamers, R. L. (2022). Optimizing antibiotic use in Indonesia: A systematic review and evidence synthesis to inform opportunities for intervention. The Lancet Regional Health–Southeast Asia, 2, 100013. https://doi.org/10.1016/j.lansea.2022.05.002.
Lincoln, Y. S., & Guba, E. G. (1985). Naturalistic inquiry. SAGE Publications.
Mackey, T. K., Jarmusch, A. K., Xu, Q., Sun, K., Lu, A., Aguirre, S., ... & Dorrestein, P. C. (2022). Multifactor quality and safety analysis of antimicrobial drugs sold by online pharmacies that do not require a prescription: Multiphase observational, content analysis, and product evaluation study. JMIR Public health and surveillance, 8(12), e41834. https://doi.org/10.2196/41834
Mallah, N., Orsini, N., Figueiras, A., & Takkouche, B. (2022). Education level and misuse of antibiotics in the general population: A systematic review and dose–response meta-analysis. Antimicrobial Resistance & Infection Control, 11(1), 24. https://doi.org/10.1186/s13756-022-01063-5
Malterud, K., Siersma, V. D., & Guassora, A. D. (2016). Sample size in qualitative interview studies: Guided by information power. Qualitative Health Research, 26(13), 1753–1760. https://doi.org/10.1177/1049732315617444
Miles, M. B., Huberman, A. M., & Saldaña, J. (2020). Qualitative data analysis: A methods sourcebook (4th ed.). SAGE Publications.
Monnier, A. A., Do, N. T., Asante, K. P., Afari-Asiedu, S., Khan, W. A., Munguambe, K., ... & Wafawanaka, F. (2023). Is this pill an antibiotic or a painkiller? Improving the identification of oral antibiotics for better use. The Lancet Global Health, 11(8), e1308-e1313. https://doi.org/10.1016/S2214-109X(23)00258-9
Msughter, A. E., & Idris, M. K. (2023). Focus group discussions with rural women in yobe state on information services for community engagement on development issues in Nigeria. Journal of African Conflicts and Peace Studies, 5(2), 9. https://digitalcommons.usf.edu/jacaps/vol5/iss2/9/
Naing, S. Y., Schneiders, M. L., Ningrum, D., Nurdianti, T., Severin, J., Peeters Grietens, K., Wagenaar, J. A., & Karuniawati, A. (2026). “Miss, I want itchy medicine”: Understanding what, why, and how antibiotics are used in Central Java Province, Indonesia through the drug bag method. PLOS Global Public Health, 6(3), e0005933. https://doi.org/10.1371/journal.pgph.0005933.
Naveed, M., Chaudhry, Z., Bukhari, S. A., Meer, B., & Ashraf, H. (2020). Antibiotics resistance mechanism. In Antibiotics and Antimicrobial Resistance Genes in the Environment (pp. 292-312). Elsevier. https://doi.org/10.1016/B978-0-12-818882-8.00019-X
O’Brien, B. C., Harris, I. B., Beckman, T. J., Reed, D. A., & Cook, D. A. (2014). Standards for reporting qualitative research: A synthesis of recommendations. Academic Medicine, 89(9), 1245–1251. https://doi.org/10.1097/ACM.0000000000000388
Rocha, V., Estrela, M., Neto, V., Roque, F., Figueiras, A., & Herdeiro, M. T. (2022). Educational interventions to reduce prescription and dispensing of antibiotics in primary care: a systematic review of economic impact. Antibiotics, 11(9), 1186. https://doi.org/10.3390/antibiotics11091186
Sharma, S., Chauhan, A., Ranjan, A., Mathkor, D. M., Haque, S., Ramniwas, S., ... & Yadav, V. (2024). Emerging challenges in antimicrobial resistance: Implications for pathogenic microorganisms, novel antibiotics, and their impact on sustainability. Frontiers in microbiology, 15, 1403168. https://doi.org/10.3389/fmicb.2024.1403168
Tong, A., Sainsbury, P., & Craig, J. (2007). Consolidated criteria for reporting qualitative research: A 32-item checklist for interviews and focus groups. International Journal for Quality in Health Care, 19(6), 349–357. https://doi.org/10.1093/intqhc/mzm042
Tumwine, C., Aggleton, P., & Bell, S. (2019). Accessing HIV treatment and care services in fishing communities around Lake Victoria in Uganda: Mobility and transport challenges. African Journal of AIDS Research, 18(3), 205-214. https://doi.org/10.2989/16085906.2019.1648306
Weiss, D. J., Nelson, A., Vargas-Ruiz, C. A., Gligorić, K., Bavadekar, S., Gabrilovich, E., ... & Gething, P. W. (2020). Global maps of travel time to healthcare facilities. Nature medicine, 26(12), 1835-1838. https://doi.org/10.1038/s41591-020-1059-1
Widayati, A., Suryawati, S., de Crespigny, C., & Hiller, J. E. (2015). Beliefs about the use of nonprescribed antibiotics among people in Yogyakarta City, Indonesia: A qualitative study based on the theory of planned behavior. Asia-Pacific Journal of Public Health, 27(2), NP402–NP413. https://doi.org/10.1177/1010539512445052
World Health Organization. (2023). Antimicrobial resistance. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
Downloads
Published
How to Cite
Issue
Section
Citation Check
License
Copyright (c) 2026 Arung: Community Health Insight

This work is licensed under a Creative Commons Attribution 4.0 International License.






